A printed circuit board has thousands of vias to drill. The drill bit has to visit each one and come home (to swap to the next bit, often). The tour length determines machine time, which is the dominant cost on a PCB line. The same shape — visit every point once, minimize travel — controls 3D printer head paths, CNC milling, semiconductor wafer probing, warehouse pick-paths, and chemistry-lab autosamplers. Concorde, the flagship academic traveling salesman solver, has solved instances with 85,900 cities (the design of a custom VLSI chip in 2006); commercial solvers like FICO Xpress and Gurobi handle 100K-point routing with branch-and-cut and Lin-Kernighan heuristics.
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PCB drilling and 3D printing
Anything where a tool head visits every spot once and returns home is a Hamilton circuit — usually with edge weights, making it the traveling salesman problem.